Which class of drugs is described as disease-modifying therapy for multiple sclerosis?

• A. Biologics
• B. Immunomodulating drugs, synthetic myelin drugs
• C. Antihistamines
• D. Vasodilators

Answer: (B)

In multiple sclerosis, disease-modifying therapies are designed to alter the immune process that damages myelin, not just treat symptoms. These are immunomodulating drugs that adjust the immune response—reducing autoimmune attack on the CNS, lowering relapse rates, and slowing disability progression. They can include synthetic compounds as well as biologic agents that target specific immune pathways. The other options don’t aim to change the disease course: antihistamines treat allergies, vasodilators affect blood vessels, and while biologics can be disease-modifying, the standard class most clearly described as disease-modifying therapy for MS is immunomodulating drugs, including synthetic myelin–targeted therapies.