Which of the following is a symptom of renal failure?

• A. Fatigue
• B. Depression
• C. Jugular Vein Distention
• D. Ulcers In Mouth And Throat

Answer: (A)

Fatigue is a hallmark of renal failure because the kidneys are not only filtering wastes but also signaling the body to make erythropoietin, which stimulates red blood cell production. When erythropoietin falls short, anemia develops, reducing oxygen delivery to tissues and leading to persistent tiredness. Additionally, the buildup of waste products (uremia) and electrolyte imbalances further sap energy and cause a general sense of weakness. These factors tend to present early in kidney dysfunction, making fatigue a common and characteristic symptom.

Depression can occur with chronic illness but isn’t specific to kidney failure. Jugular vein distention points to volume overload or heart problems rather than a kidney-specific symptom. Ulcers in the mouth and throat can occur in advanced uremia, but they are less common and typically accompany other uremic signs.